Vinblastine VS. nitrogen mustard therapy of Hodgkin's disease
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منابع مشابه
Nitrogen Mustard Therapy in Hodgkin ’ S Disease Analysis of Fifty
INTRODUCTION M USTARD gas was first discovered by Ritchie in 1854 and prepared for manufacture by Meyer in a 886. It was first used as a war gas by the Germans at Ypres in the spring of 1915. Five hundred deaths and 14,2.76 casualties resulted from this initial attack. By the end of the war, there was a total of 400,000 casualties from mustard gas poisoning. The clinical course of these victims...
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By JEANNE C. BATEMAN,* M.D., CALVIN T. KLOPP, M.D., and J. KEITH CROMER, M.D. M ETHYL his (beta-chloroethyl) amine hydrochloride (referred to hereafter as HN2) has been established as an effective agent in the palliative therapy of certain malignant diseases, includ!ing Hodgkin’s dhsease, lymphosarcoma, mycosis fungoides, chronic leukemia, polycythemia and some cases of inoperable carcinoma of ...
متن کاملNitrogen Mustard Therapy in Hodgkin ’ S Disease Analysis of Fifty Consecutive Cases
INTRODUCTION M USTARD gas was first discovered by Ritchie in 1854 and prepared for manufacture by Meyer in a 886. It was first used as a war gas by the Germans at Ypres in the spring of 1915. Five hundred deaths and 14,2.76 casualties resulted from this initial attack. By the end of the war, there was a total of 400,000 casualties from mustard gas poisoning. The clinical course of these victims...
متن کاملMassive nitrogen mustard therapy in Hodgkin's disease with protection of bone marrow by tourniquets.
By MARCEL E. CONRAD, JR. AND \VILLIAM H. CROSBY T HE BENEFICIAL EFFECTS of nitrogen mustard in the treatment of Hodgkin’s disease have been well documented. Unfortunately, as the disease progresses increasing dosage and frequency of administration are necessary to produce tumor regression. The amount of therapy administered is limited by severe depression of the bone marrow with the development of
متن کاملExperiences in the Treatment of Neoplastic Disease with Nitrogen Mustard *
The reintroduction of poison gas in warfare by the Germans in 1915 stimulated experimental studies, both in the clinic and in the animal laboratory, on the effect of these agents upon various body structures. Between 1919 and 1921 several reports1'5,6,78 appeared describing the changes produced by mustard gas. The recent world conflict stimulated further research relating to the properties of t...
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ژورنال
عنوان ژورنال: Cancer
سال: 1968
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(196808)22:2<473::aid-cncr2820220227>3.0.co;2-i